THE VIEW OF PEDIATRIC NEPHROTIC SYNDROME AS A PODOCYTOPATHY

The View of Pediatric Nephrotic Syndrome as a Podocytopathy

Nephrotic syndrome (NS) is a complex clinical entity characterized by proteinuria, hypoalbuminemia, and edema.In this review, we propose the view Tape Dispensers of NS as a podocytopathy, highlighting the importance of understanding the role of podocytes in the development of this condition.We discuss the various etiologies of NS, ranging from cong

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Search for a platelet-activating factor receptor in the Trypanosoma cruzi proteome: a potential target for Chagas disease chemotherapy

Chagas disease (CD) causes the highest burden of parasitic diseases in the Western Hemisphere and is therefore a priority for drug research and development.Platelet-activating factor (PAF) causes the CD parasite Trypanosoma cruzi to differentiate, which suggests that the parasite may express PAF receptors.Here, we explored the T.cruzi proteome for

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Intranasal influenza virus-vectored vaccine offers protection against clade 2.3.4.4b H5N1 infection in small animal models

Abstract The highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic in aquatic birds since 1997, causing outbreaks in domestic poultry and occasional human infections worldwide.Recently, the cross-species transmission of a new reassortant variant from clade 2.3.4.4b Vases of H5N1 to cattle in the US has heightened concerns regarding t

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